sage flower

Serene Skin Sage

For an active skin barrier


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A vegetal story

A key medicinal plant: the sage
salvia officinalis, Lamiaceae

Sage is a small herbaceous perennial from the dry regions around the Mediterranean. It is an aromatic plant that has been well-known since antiquity for its medicinal properties. Its name comes from the verb to save (salvare in Latin). It is said to be antiseptic, tonic, antiperspirant, soothing for the mucous membranes and to improve digestion. It is combined with other plants to create a range of remedies. Now cultivated in several European and American countries, it is also used as a flavouring in cooking, particularly in marinades and to season game.

Because our skin is our first defence against visible and invisible external threats, it is essential to keep its protective and repair mechanisms functions in optimal condition.
Skin imbalances can be caused by microbial or physico-chemical threats.

For soothed skin that radiates well-being.

Marketing claims

Enhances complexion

Unifies the complexion, increases radiance.

Reconstructing, lipid-replenishing

Helps to homogenize and restructure the composition of the stratum corneum.


Promotes cell renewal.

Protection and repair

Helps to rebuild, strengthen and unify the skin barrier.
Strengthens immune anti-microbial defences.


Rebalances the components of the skin flora.

Soothing, anti-inflammatory

Reduces inflammatory processes, calms red skin.

  • INCI name of cells: Salvia officinalis callus extract (in progress)
  • Aspect: liquid
  • Form: cells (20%) in glycerin or sunflower oil (80%)
  • Concentration: starting at 0.5%

How it works ?

Serene Skin Sage: a skin barrier in perpetual renewal

Our skin has two opposing characteristics:

it is both open and closed to the external environment. Its primary role is to protect us against water loss, but it has many other roles: sensory, emotional, protection against external threats, temperature regulation and hormone synthesis. Because it is protective, the epidermis is referred to as a "skin barrier".

The epidermis is not an assembly of inert components; on the contrary, it is living and constantly renewed: bacteria proliferate on the surface, living and dying depending on external conditions and on our bodies. In the lower layers, a cellular differentiation process takes place: moving up to the surface, living cells called keratinocytes, gradually transform into corneocytes, dead keratinized cells, and then shed. Our skin is thus constantly shedding and secreting mucus. Paradoxically, it is this incessant renewal of its composition that enables the skin to retain its full functionality. It is a perpetually renewed balance.

The skin barrier and its external aggressions

diagram of the skin barrier and its external aggressions

And it is essential to maintain it because in terms of threats, the skin has to face several types: physical (UV, temperatures, etc.), chemical and microbial (viruses, fungi, pollution, allergens, etc.), and internal imbalances (stress) that trigger oxidation and inflammation that ultimately damages cells. To combat them, the epidermis uses several defence mechanisms, ranging from simple to highly complex.

Serene Skin Sage: helps skin combat multiple external threats

Serene Skin Sage acts on three types of epidermal defence: physical, chemical and immune, which follow one another in the skin’s lines of defence, from the surface into the living layers of the epidermis.

Through an effective physical barrier

Healthy skin is first of all made up of a homogeneous, thick (100 microns), uniform stratum corneum, with a balanced lipid composition, which prevents penetration by foreign agents and retains moisture. However, skin ageing and other imbalances slow down epidermal differentiation and therefore cornification.
By acting on cell differentiation, lipid synthesis and key proteins in cornification,

Serene Skin Sage strengthens the corneocyte structure at the skin’s surface.

Through a high performance chemical barrier

The skin’s surface has to maintain a balance of different kinds of bacteria and face pathogens: too frequent washing and lack of exposure to certain microbes or viruses can lower the level of our chemical defences, the presence of good bacteria then decreases, and the release of anti-microbial peptides is less effective.
By acting on the microbiota’s key bacteria and stimulating the production of anti-microbial peptides,

Serene Skin Sage enhances the action of the skin's anti-microbial weapons.

By a controlled immunomodulatory and inflammatory barrier

The final line of defence is provided by immune function cells and the associated inflammatory mediators. They are the last resort in the fight against pathogens and stopping any damage. Several inflammatory mediators are markers of their action, such as TNF-alpha. Others signal the intrusion of the pathogens.
Through its action on key inflammatory mediators involved in the immune system defence mechanisms,

Serene Skin Sage strengthens the immune response and reduces skin inflammation.

Thanks to a triple reinforcement action of the cutaneous barrier, Serene Skin Sage helps to enhance radiance and soothe the skin.

Clinical study

A more uniform, radiant complexion after 28 days

Skin well-being is restored – radiance, evenness, reduced redness (2 applications a day) after 28 days
  • Increased skin radiance of 30%
  • Increased brightness of 27%
  • Increased uniformity in skin tone of 21%
  • Increased soothing effect of 30%
  • Reduction of redness (cheeks) of 26%
Declaration of the panel
  • 100% of women reported that their skin looked purified
  • 95% of women reported that and their complexion was radiant
  • 90% of women reported that their skin was less sensitive
Study details

Test carried out for 28 days on a sample of 20 women aged 20 years to 65 years. Application twice a day. Emulsion with 0.5% de Serene Skin Sage (20% cells)

Improvement of the skin tone

graph of improvement of the skin tone